Atrial Fibrillation and Percutaneous Coronary Intervention: A Case-based Guide to Oral Anticoagulation, Antiplatelet Therapy and Stenting
Andrea Rubboli, Gregory YH LipThis book considers paradigmatic clinical cases in order to cast
light on key issues relating to elective or emergency stent implantation
and the use of oral anticoagulation (OAC) in patients with atrial
fibrillation. The topics addressed include the optimal periprocedural
antithrombotic treatment (uninterrupted vs interrupted OAC,
intraprocedural use of heparin and glycoprotein IIb/IIIa inhibitors,
etc.), the most appropriate type of stent (bare metal vs drug eluting vs
“bioactive”), the optimal regimen (e.g., triple therapy of OAC,
aspirin, and clopidogrel vs the combination of OAC and a single
antiplatelet agent), and the most suitable duration of the
antithrombotic treatment prescribed at discharge (1 vs 6–12 months).
The case-based management recommendations will be of wide practical
value in the current health care context, where percutaneous coronary
intervention is available even to patients with relevant co-morbidities,
such as those warranting long-term OAC, and the indications for OAC are
much broader than in the past. The book will appeal especially to
clinical and interventional cardiologists, internal medicine
specialists, hematologists, and family physicians and will also be of
interest to cardiology and internal medicine residents and fellows.